5H2U: Crystal structure of PTK6 Kinase Domain complexed with Dasatinib

PDB ID: 5H2UDownload
MMDB ID: 146103
PDB Deposition Date: 2016/10/18
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.24  Å
Source Organism:
Similar Structures:
Biological Unit for 5H2U: monomeric; determined by author and by software (PISA)
Molecular Components in 5H2U
Label Count Molecule
Protein (1 molecule)
1
Protein-tyrosine Kinase 6
(Gene symbol: PTK6)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDEN-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE
2
3
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303