5GTY: Crystal structure of EGFR 696-1022 T790M in complex with LXX-6-26

PDB ID: 5GTYDownload
MMDB ID: 154210
PDB Deposition Date: 2016/8/23
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 3.14  Å
Source Organism:
Similar Structures:
Biological Unit for 5GTY: tetrameric; determined by author
Molecular Components in 5GTY
Label Count Molecule
Proteins (4 molecules)
4
Epidermal Growth Factor Receptor
(Gene symbol: EGFR)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
4
1-[(3R)-3-[4-azanyl-3-[3-chloranyl-4-[(6-methylpyridin-2-yl)methoxy]phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one1-[(3R)-3-[4-azanyl-3-[3-chloranyl-4-[(6-methylpyridin-2-yl)methoxy]phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one
2
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303