5GON: Structures of a beta-lactam bridged analogue in complex with tubulin

PDB ID: 5GONDownload
MMDB ID: 148493
PDB Deposition Date: 2016/7/28
Updated in MMDB: 2024/03
Experimental Method:
x-ray diffraction
Resolution: 2.48  Å
Source Organism:
Rattus norvegicus▼
Similar Structures:
Biological Unit for 5GON: hexameric; determined by author
Molecular Components in 5GON
Label Count Molecule
Proteins (6 molecules)
2
Tubulin Alpha-1b Chain
Molecule annotation
2
Tubulin Beta-2b Chain
Molecule annotation
1
Stathmin-4
Molecule annotation
1
Uncharacterized Protein
Molecule annotation
Chemicals and Non-standard biopolymers (29 molecules)
1
2
GUANOSINE-5'-TRIPHOSPHATEGUANOSINE-5'-TRIPHOSPHATE
2
5
MAGNESIUM IONMAGNESIUM ION
3
12
GLYCEROLGLYCEROL
4
3
CALCIUM IONCALCIUM ION
5
2
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
6
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
7
1
(3R,4R)-4-(4-methoxy-3-oxidanyl-phenyl)-3-methyl-1-(3,4,5-trimethoxyphenyl)azetidin-2-one(3R,4R)-4-(4-methoxy-3-oxidanyl-phenyl)-3-methyl-1-(3,4,5-trimethoxyphenyl)azetidin-2-one
8
3
IMIDAZOLEIMIDAZOLE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303