5GMP: Crystal structure of EGFR 696-1022 T790M in complex with XTF-262

PDB ID: 5GMPDownload
MMDB ID: 152072
PDB Deposition Date: 2016/7/14
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.797  Å
Source Organism:
Similar Structures:
Biological Unit for 5GMP: monomeric; determined by author
Molecular Components in 5GMP
Label Count Molecule
Protein (1 molecule)
1
Epidermal Growth Factor Receptor
(Gene symbol: EGFR)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-[3-[2-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-5-methyl-7-oxidanylidene-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamideN-[3-[2-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-5-methyl-7-oxidanylidene-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303