5G4M: Crystal structure of the p53 cancer mutant Y220C in complex with a monofluorinated derivative of the small molecule stabilizer Phikan083

PDB ID: 5G4MDownload
MMDB ID: 175291
PDB Deposition Date: 2016/5/13
Updated in MMDB: 2019/06
Experimental Method:
x-ray diffraction
Resolution: 1.38  Å
Source Organism:
Similar Structures:
Biological Unit for 5G4M: monomeric; determined by software (PISA)
Molecular Components in 5G4M
Label Count Molecule
Protein (1 molecule)
1
Cellular Tumor Antigen P53
(Gene symbol: TP53)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
ZINC IONZINC ION
2
1
1-[9-(2-fluoroethyl)-9H-carbazol-3-yl]-N-methylmethanamine1-[9-(2-fluoroethyl)-9H-carbazol-3-yl]-N-methylmethanamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303