5FZL: Crystal structure of the catalytic domain of human JARID1B in complex with 3D fragment 3-methyl-N-pyridin-4-yl-1,2-oxazole-5-carboxamide (N09954a) (ligand modelled based on PANDDA event map, SGC - Diamond I04-1 fragment screening)

PDB ID: 5FZLDownload
MMDB ID: 138165
PDB Deposition Date: 2016/3/14
Updated in MMDB: 2016/04
Experimental Method:
x-ray diffraction
Resolution: 2.55  Å
Source Organism:
Similar Structures:
Biological Unit for 5FZL: monomeric; determined by author and by software (PISA)
Molecular Components in 5FZL
Label Count Molecule
Protein (1 molecule)
1
Lysine-specific Demethylase 5B
(Gene symbol: KDM5B)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
1
ZINC IONZINC ION
2
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
1
MANGANESE (II) IONMANGANESE (II) ION
4
10
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
1
3-methyl-N-(pyridin-4-yl)-1,2-oxazole-5-carboxamide3-methyl-N-(pyridin-4-yl)-1,2-oxazole-5-carboxamide
6
1
CHLORIDE IONCHLORIDE ION
7
1
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303