5FYU: Crystal structure of the catalytic domain of human JARID1B in complex with 3D fragment 3-Amino-4-methyl-1,3-dihydro-2H-indol-2-one (N10042a)

PDB ID: 5FYUDownload
MMDB ID: 137746
PDB Deposition Date: 2016/3/9
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.06  Å
Source Organism:
Similar Structures:
Biological Unit for 5FYU: monomeric; determined by author and by software (PISA)
Molecular Components in 5FYU
Label Count Molecule
Protein (1 molecule)
1
Lysine-specific Demethylase 5B
(Gene symbol: KDM5B)
Molecule annotation
Chemicals and Non-standard biopolymers (22 molecules)
1
1
ZINC IONZINC ION
2
2
MANGANESE (II) IONMANGANESE (II) ION
3
1
PHOSPHATE IONPHOSPHATE ION
4
13
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
3
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
6
1
(3R)-3-azanyl-4-methyl-1,3-dihydroindol-2-one(3R)-3-azanyl-4-methyl-1,3-dihydroindol-2-one
7
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303