5FVU: Structure of human nNOS R354A G357D mutant heme domain in complex with 4-methyl-6-(2-(5-(4-methylpiperazin-1-yl)pyridin-3-yl)ethyl) pyridin-2-amine

PDB ID: 5FVUDownload
MMDB ID: 140015
PDB Deposition Date: 2016/2/10
Updated in MMDB: 2016/06
Experimental Method:
x-ray diffraction
Resolution: 2.224  Å
Source Organism:
Similar Structures:
Biological Unit for 5FVU: dimeric; determined by author and by software (PISA)
Molecular Components in 5FVU
Label Count Molecule
Proteins (2 molecules)
2
Nitric Oxide Synthase, Brain
(Gene symbol: NOS1)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
2
5,6,7,8-TETRAHYDROBIOPTERIN5,6,7,8-TETRAHYDROBIOPTERIN
3
2
4-methyl-6-(2-(5-(4-methylpiperazin-1-yl)pyridin-3-yl)ethyl)pyridin-2-amine4-methyl-6-(2-(5-(4-methylpiperazin-1-yl)pyridin-3-yl)ethyl)pyridin-2-amine
4
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303