5FUC: Biophysical and cellular characterisation of a junctional epitope antibody that locks IL-6 and gp80 together in a stable complex: implications for new therapeutic strategies

PDB ID: 5FUCDownload
MMDB ID: 146700
PDB Deposition Date: 2016/1/25
Updated in MMDB: 2018/11
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Camelus dromedarius▼
Similar Structures:
Biological Unit for 5FUC: trimeric; determined by author and by software (PQS)
Molecular Components in 5FUC
Label Count Molecule
Proteins (3 molecules)
1
Interleukin-6
Molecule annotation
1
Interleukin-6 Receptor Subunit Alpha, Interleukin-6 Receptor
Molecule annotation
1
Vhh6
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303