5FTJ: Cryo-EM structure of human p97 bound to UPCDC30245 inhibitor

PDB ID: 5FTJDownload
MMDB ID: 136078
PDB Deposition Date: 2016/1/14
Updated in MMDB: 2018/10
Experimental Method:
electron microscopy
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 5FTJ: hexameric; determined by author
Molecular Components in 5FTJ
Label Count Molecule
Proteins (6 molecules)
6
Transitional Endoplasmic Reticulum Atpase
(Gene symbol: VCP)
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
12
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
2
6
1-(3-(5-FLUORO-1H-INDOL-2-YL)PHENYL)PIPERIDIN-4-YL)(2-(4-ISOPROPYL-PIPERAZIN1-YL)ETHYL)-CARBAMATE1-(3-(5-FLUORO-1H-INDOL-2-YL)PHENYL)PIPERIDIN-4-YL)(2-(4-ISOPROPYL-PIPERAZIN1-YL)ETHYL)-CARBAMATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303