5FM2: Crystal structure of hyper-phosphorylated RET kinase domain with (proximal) juxtamembrane segment

PDB ID: 5FM2Download
MMDB ID: 145952
PDB Deposition Date: 2015/10/30
Updated in MMDB: 2016/12
Experimental Method:
x-ray diffraction
Resolution: 3.3  Å
Source Organism:
Similar Structures:
Biological Unit for 5FM2: dimeric; determined by author and by software (PISA)
Molecular Components in 5FM2
Label Count Molecule
Proteins (2 molecules)
2
Proto-oncogene Tyrosine-protein Kinase Receptor RET
(Gene symbol: RET)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
1-TER-BUTYL-3-P-TOLYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE1-TER-BUTYL-3-P-TOLYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303