5FJH: Crystal structure of human JMJD2C catalytic domain in complex with epitherapuetic compound 2-(((2-((2-(dimethylamino)ethyl) (ethyl)amino) -2-oxoethyl)amino)methyl)isonicotinic acid

PDB ID: 5FJHDownload
MMDB ID: 133596
PDB Deposition Date: 2015/10/9
Updated in MMDB: 2015/10
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 5FJH: monomeric; determined by author and by software (PISA)
Molecular Components in 5FJH
Label Count Molecule
Protein (1 molecule)
1
Lysine-specific Demethylase 4C
(Gene symbol: KDM4C)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
NICKEL (II) IONNICKEL (II) ION
2
1
2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid
3
1
ZINC IONZINC ION
4
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303