5FI6: Crystal structure of human GAC in complex with inhibitor UPGL_00011: 2-phenyl-~{N}-[5-[[(3~{S})-1-[5-(2-phenylethanoylamino)-1,3,4-thiadiazol-2-yl]pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]ethanamide

PDB ID: 5FI6Download
MMDB ID: 139151
PDB Deposition Date: 2015/12/22
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 2.52  Å
Source Organism:
Similar Structures:
Biological Unit for 5FI6: tetrameric; determined by author and by software (PISA)
Molecular Components in 5FI6
Label Count Molecule
Proteins (4 molecules)
4
Glutaminase Kidney Isoform, Mitochondrial
(Gene symbol: GLS)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
2-phenyl-~{N}-[5-[[(3~{S})-1-[5-(2-phenylethanoylamino)-1,3,4-thiadiazol-2-yl]pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]ethanamide2-phenyl-~{N}-[5-[[(3~{S})-1-[5-(2-phenylethanoylamino)-1,3,4-thiadiazol-2-yl]pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]ethanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303