5FDR: Mcl-1 complexed with small molecule inhibitor

PDB ID: 5FDRDownload
MMDB ID: 137032
PDB Deposition Date: 2015/12/16
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 5FDR: monomeric; determined by author and by software (PISA)
Molecular Components in 5FDR
Label Count Molecule
Protein (1 molecule)
1
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1
(Gene symbol: MCL1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
4
5-[[6-chloranyl-3-[3-(4-chloranyl-3,5-dimethyl-phenoxy)propyl]-7-(3,5-dimethyl-1~{H}-pyrazol-4-yl)-1~{H}-indol-2-yl]carbonylsulfamoyl]furan-2-carboxylic acid5-[[6-chloranyl-3-[3-(4-chloranyl-3,5-dimethyl-phenoxy)propyl]-7-(3,5-dimethyl-1~{H}-pyrazol-4-yl)-1~{H}-indol-2-yl]carbonylsulfamoyl]furan-2-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303