5FDI: Crystal structure of Human Carbonic Anhydrase II with the anticonvulsant sulfamide JNJ-26990990 and its S,S-dioxide analog

PDB ID: 5FDIDownload
MMDB ID: 139327
PDB Deposition Date: 2015/12/16
Updated in MMDB: 2016/06
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
Similar Structures:
Biological Unit for 5FDI: monomeric; determined by author and by software (PISA)
Molecular Components in 5FDI
Label Count Molecule
Protein (1 molecule)
1
Carbonic Anhydrase 2
(Gene symbol: CA2)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
ZINC IONZINC ION
2
1
1,1-bis(oxidanylidene)-3-[(sulfamoylamino)methyl]-1-benzothiophene1,1-bis(oxidanylidene)-3-[(sulfamoylamino)methyl]-1-benzothiophene
3
1
GLYCEROLGLYCEROL
4
1
4-(HYDROXYMERCURY)BENZOIC ACID4-(HYDROXYMERCURY)BENZOIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303