5FCT: Mouse thymidylate synthase in ternary complex with FdUMP and methylenetetrahydrofolate

PDB ID: 5FCTDownload
MMDB ID: 144281
PDB Deposition Date: 2015/12/15
Updated in MMDB: 2016/10
Experimental Method:
x-ray diffraction
Resolution: 1.55  Å
Source Organism:
Similar Structures:
Biological Unit for 5FCT: dimeric; determined by author and by software (PISA)
Molecular Components in 5FCT
Label Count Molecule
Proteins (2 molecules)
2
Thymidylate Synthase
(Gene symbol: Tyms)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE
2
2
5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303