5FC4: Mcl-1 complexed with small molecule inhibitor

PDB ID: 5FC4Download
MMDB ID: 137806
PDB Deposition Date: 2015/12/14
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.5  Å
Source Organism:
Similar Structures:
Biological Unit for 5FC4: monomeric; determined by author and by software (PISA)
Molecular Components in 5FC4
Label Count Molecule
Protein (1 molecule)
1
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1
(Gene symbol: MCL1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
6-chloranyl-~{N}-methylsulfonyl-3-(3-naphthalen-1-yloxypropyl)-1~{H}-indole-2-carboxamide6-chloranyl-~{N}-methylsulfonyl-3-(3-naphthalen-1-yloxypropyl)-1~{H}-indole-2-carboxamide
2
1
2-[5-[1,1,2,2-tetrakis(fluoranyl)ethyl]-1~{H}-pyrazol-3-yl]phenol2-[5-[1,1,2,2-tetrakis(fluoranyl)ethyl]-1~{H}-pyrazol-3-yl]phenol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303