5F91: Fumarate hydratase of Mycobacterium tuberculosis in complex with formate and allosteric modulator (N-(5-(azepan-1-ylsulfonyl)-2-methoxyphenyl)-2-(4-oxo-3,4-dihydrophthalazin-1-yl)acetamide)

PDB ID: 5F91Download
MMDB ID: 140251
PDB Deposition Date: 2015/12/9
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 1.998  Å
Source Organism:
Similar Structures:
Biological Unit for 5F91: tetrameric; determined by author and by software (PISA)
Molecular Components in 5F91
Label Count Molecule
Proteins (4 molecules)
4
Fumarate Hydratase Class II
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
~{N}-[5-(azepan-1-ylsulfonyl)-2-methoxy-phenyl]-2-(4-oxidanylidene-3~{H}-phthalazin-1-yl)ethanamide~{N}-[5-(azepan-1-ylsulfonyl)-2-methoxy-phenyl]-2-(4-oxidanylidene-3~{H}-phthalazin-1-yl)ethanamide
2
5
CHLORIDE IONCHLORIDE ION
3
1
FORMIC ACIDFORMIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303