5F6L: The crystal structure of MLL1 (N3861I/Q3867L) in complex with RbBP5 and Ash2L

PDB ID: 5F6LDownload
MMDB ID: 136784
PDB Deposition Date: 2015/12/6
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 5F6L: trimeric; determined by author
Molecular Components in 5F6L
Label Count Molecule
Proteins (3 molecules)
1
Retinoblastoma-binding Protein 5
(Gene symbol: RBBP5)
Molecule annotation
1
Set1/ash2 Histone Methyltransferase Complex Subunit Ash2
(Gene symbol: ASH2L)
Molecule annotation
1
Histone-lysine N-methyltransferase 2A
(Gene symbol: KMT2A)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
2
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303