5F3E: Crystal structure of human KDM4A in complex with compound 54a

PDB ID: 5F3EDownload
MMDB ID: 135807
PDB Deposition Date: 2015/12/2
Updated in MMDB: 2016/03
Experimental Method:
x-ray diffraction
Resolution: 2.16  Å
Source Organism:
Similar Structures:
Biological Unit for 5F3E: monomeric; determined by author
Molecular Components in 5F3E
Label Count Molecule
Protein (1 molecule)
1
Lysine-specific Demethylase 4A
(Gene symbol: KDM4A)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
ZINC IONZINC ION
2
1
8-[4-[2-[4-(4-chlorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one8-[4-[2-[4-(4-chlorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one
3
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303