5F20: Structure of TYK2 with inhibitor 4: 3-azanyl-5-(2-methylphenyl)-7-(1-methylpyrazol-3-yl)-1~{H}-pyrazolo[4,3-c]pyridin-4-one

PDB ID: 5F20Download
MMDB ID: 135534
PDB Deposition Date: 2015/12/1
Updated in MMDB: 2024/03
Experimental Method:
x-ray diffraction
Resolution: 2.91  Å
Source Organism:
Similar Structures:
Biological Unit for 5F20: monomeric; determined by author and by software (PISA)
Molecular Components in 5F20
Label Count Molecule
Protein (1 molecule)
1
Non-receptor Tyrosine-protein Kinase Tyk2
(Gene symbol: TYK2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-azanyl-5-(2-methylphenyl)-7-(1-methylpyrazol-3-yl)-1~{H}-pyrazolo[4,3-c]pyridin-4-one3-azanyl-5-(2-methylphenyl)-7-(1-methylpyrazol-3-yl)-1~{H}-pyrazolo[4,3-c]pyridin-4-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303