5F1V: biomimetic design results in a potent allosteric inhibitor of dihydrodipicolinate synthase from Campylobacter jejuni

PDB ID: 5F1VDownload
MMDB ID: 136606
PDB Deposition Date: 2015/11/30
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 5F1V: tetrameric; determined by author and by software (PISA)
Molecular Components in 5F1V
Label Count Molecule
Proteins (4 molecules)
4
4-hydroxy-tetrahydrodipicolinate Synthase
(Gene symbol: dapA)
Molecule annotation
Chemicals and Non-standard biopolymers (17 molecules)
1
4
(2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid(2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid
2
3
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
3
9
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303