5F1U: biomimetic design results in a potent allosteric inhibitor of dihydrodipicolinate synthase from Campylobacter jejuni

PDB ID: 5F1UDownload
MMDB ID: 136605
PDB Deposition Date: 2015/11/30
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.35  Å
Source Organism:
Similar Structures:
Biological Unit for 5F1U: tetrameric; determined by author and by software (PISA)
Molecular Components in 5F1U
Label Count Molecule
Proteins (4 molecules)
4
4-hydroxy-tetrahydrodipicolinate Synthase
(Gene symbol: dapA)
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
2
(2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid(2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid
2
1
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
3
10
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
CHLORIDE IONCHLORIDE ION
5
1
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303