5EZZ: Crystal Structure Of Bace-1 In Complex With (4s)-4-[3-(5-chloro-3- Pyridyl)phenyl]-4-[4-(difluoromethoxy)-3-methyl-phenyl]-5h-oxazol-2- Amine

PDB ID: 5EZZDownload
MMDB ID: 136769
PDB Deposition Date: 2015/11/27
Updated in MMDB: 2016/05
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 5EZZ: monomeric; determined by author and by software (PISA)
Molecular Components in 5EZZ
Label Count Molecule
Protein (1 molecule)
1
Beta-secretase 1
(Gene symbol: BACE1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
(4~{s})-4-[4-[bis(Fluoranyl)methoxy]-3-Methyl-Phenyl]-4-[3-(5-Chloranylpyridin-3-Yl)phenyl]-5~{h}-1,3-Oxazol-2-Amine(4~{s})-4-[4-[bis(Fluoranyl)methoxy]-3-Methyl-Phenyl]-4-[3-(5-Chloranylpyridin-3-Yl)phenyl]-5~{h}-1,3-Oxazol-2-Amine
2
1
Dimethyl SulfoxideDimethyl Sulfoxide
3
2
Sodium IonSodium Ion
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303