5EZV: X-ray crystal structure of AMP-activated protein kinase alpha-2/alpha-1 RIM chimaera (alpha-2(1-347)/alpha-1(349-401)/alpha-2(397-end) beta-1 gamma-1) co-crystallized with C2 (5-(5-hydroxyl-isoxazol-3-yl)-furan-2-phosphonic acid)

PDB ID: 5EZVDownload
MMDB ID: 236315
PDB Deposition Date: 2015/11/26
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.99  Å
Source Organism:
Similar Structures:
Biological Unit for 5EZV: trimeric; determined by author and by software (PISA)
Molecular Components in 5EZV
Label Count Molecule
Proteins (3 molecules)
1
5'-amp-activated Protein Kinase Catalytic Subunit Alpha-2/alpha-1 RIM Swap Chimera
(Gene symbol: PRKAA2)
Molecule annotation
1
5'-amp-activated Protein Kinase Subunit Beta-1
(Gene symbol: PRKAB1)
Molecule annotation
1
5'-amp-activated Protein Kinase Subunit Gamma-1
(Gene symbol: PRKAG1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
STAUROSPORINESTAUROSPORINE
2
1
3-[4-(2-hydroxyphenyl)phenyl]-4-oxidanyl-6-oxidanylidene-7H-thieno[2,3-b]pyridine-5-carbonitrile3-[4-(2-hydroxyphenyl)phenyl]-4-oxidanyl-6-oxidanylidene-7H-thieno[2,3-b]pyridine-5-carbonitrile
3
2
5-(5-hydroxyl-isoxazol-3-yl)-furan-2-phosphonic acid5-(5-hydroxyl-isoxazol-3-yl)-furan-2-phosphonic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303