5EYK: CRYSTAL STRUCTURE OF AURORA B IN COMPLEX WITH BI 847325

PDB ID: 5EYKDownload
MMDB ID: 142420
PDB Deposition Date: 2015/11/25
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.93  Å
Source Organism:
Similar Structures:
Biological Unit for 5EYK: dimeric; determined by author and by software (PISA)
Molecular Components in 5EYK
Label Count Molecule
Proteins (2 molecules)
1
Aurora Kinase B-A
(Gene symbol: aurkb.L)
Molecule annotation
1
Inner Centromere Protein a
(Gene symbol: incenp.L)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-[(3~{Z})-3-[[[4-[(dimethylamino)methyl]phenyl]amino]-phenyl-methylidene]-2-oxidanylidene-1~{H}-indol-6-yl]-~{N}-ethyl-prop-2-ynamide3-[(3~{Z})-3-[[[4-[(dimethylamino)methyl]phenyl]amino]-phenyl-methylidene]-2-oxidanylidene-1~{H}-indol-6-yl]-~{N}-ethyl-prop-2-ynamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303