5EYC: Crystal structure of c-Met in complex with naphthyridinone inhibitor 5

PDB ID: 5EYCDownload
MMDB ID: 136425
PDB Deposition Date: 2015/11/24
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 5EYC: monomeric; determined by author and by software (PISA)
Molecular Components in 5EYC
Label Count Molecule
Protein (1 molecule)
1
Hepatocyte Growth Factor Receptor
(Gene symbol: MET)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
6-[(1~{R})-1-[8-fluoranyl-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one6-[(1~{R})-1-[8-fluoranyl-6-(3-methyl-1,2-oxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-1,6-naphthyridin-5-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303