5EXA: Small-molecule stabilization of the 14-3-3/Gab2 PPI interface

PDB ID: 5EXADownload
MMDB ID: 138946
PDB Deposition Date: 2015/11/23
Updated in MMDB: 2018/12
Experimental Method:
x-ray diffraction
Resolution: 1.95  Å
Source Organism:
Similar Structures:
Biological Unit for 5EXA: tetrameric; determined by author and by software (PISA)
Molecular Components in 5EXA
Label Count Molecule
Proteins (4 molecules)
2
14-3-3 Protein Zeta/delta
(Gene symbol: YWHAZ)
Molecule annotation
2
Grb2-associated-binding Protein 2
(Gene symbol: GAB2)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
Fusicoccin A-THF derivativeFusicoccin A-THF derivative
2
2
BENZOIC ACIDBENZOIC ACID
3
1
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303