5EWL: CRYSTAL STRUCTURE OF AMINO TERMINAL DOMAINS OF THE NMDA RECEPTOR SUBUNIT GLUN1 AND GLUN2B IN COMPLEX WITH MK-22

PDB ID: 5EWLDownload
MMDB ID: 137025
PDB Deposition Date: 2015/11/20
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.98  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 5EWL: dimeric; determined by author and by software (PISA)
Molecular Components in 5EWL
Label Count Molecule
Proteins (2 molecules)
1
Nmda Glutamate Receptor Subunit
Molecule annotation
1
Glutamate Receptor Ionotropic, Nmda 2B
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
5
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
beta-D-mannopyranosebeta-D-mannopyranose
3
5
SODIUM IONSODIUM ION
4
1
~{N}-[(1~{S},3~{S})-3-[3-[(4-methylphenyl)methyl]-1,2,4-oxadiazol-5-yl]cyclopentyl]-1~{H}-pyrazolo[3,4-d]pyrimidin-4-amine~{N}-[(1~{S},3~{S})-3-[3-[(4-methylphenyl)methyl]-1,2,4-oxadiazol-5-yl]cyclopentyl]-1~{H}-pyrazolo[3,4-d]pyrimidin-4-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303