5EW9: Crystal Structure of Aurora A Kinase Domain Bound to MK-5108

PDB ID: 5EW9Download
MMDB ID: 135798
PDB Deposition Date: 2015/11/20
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.181  Å
Source Organism:
Similar Structures:
Biological Unit for 5EW9: monomeric; determined by author and by software (PISA)
Molecular Components in 5EW9
Label Count Molecule
Protein (1 molecule)
1
Aurora Kinase a
(Gene symbol: AURKA)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-(3-chloranyl-2-fluoranyl-phenoxy)-1-[[6-(1,3-thiazol-2-ylamino)pyridin-2-yl]methyl]cyclohexane-1-carboxylic acid4-(3-chloranyl-2-fluoranyl-phenoxy)-1-[[6-(1,3-thiazol-2-ylamino)pyridin-2-yl]methyl]cyclohexane-1-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303