5EW2: Human thrombin sandwiched between two DNA aptamers: HD22 and HD1-deltaT12

PDB ID: 5EW2Download
MMDB ID: 145209
PDB Deposition Date: 2015/11/20
Updated in MMDB: 2016/12
Experimental Method:
x-ray diffraction
Resolution: 3.59  Å
Source Organism:
Similar Structures:
Biological Unit for 5EW2: tetrameric; determined by software (PISA)
Molecular Components in 5EW2
Label Count Molecule
Proteins (2 molecules)
1
Thrombin Light Chain
(Gene symbol: F2)
Molecule annotation
1
Thrombin Heavy Chain
(Gene symbol: F2)
Molecule annotation
Nucleotides(2 molecules)
1
Hd22 (27mer)
Molecule annotation
1
Hd1-deltat12
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamideD-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide
3
3
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303