5EUQ: Crystal structure of an engineered construct of phosphatidylinositol 4 kinase III beta with a potent and selective inhibitor in complex with GDP loaded Rab11

PDB ID: 5EUQDownload
MMDB ID: 136761
PDB Deposition Date: 2015/11/19
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 3.2  Å
Source Organism:
Similar Structures:
Biological Unit for 5EUQ: dimeric; determined by author and by software (PISA)
Molecular Components in 5EUQ
Label Count Molecule
Proteins (2 molecules)
1
Ras-related Protein Rab-11a
(Gene symbol: RAB11A)
Molecule annotation
1
Phosphatidylinositol 4-kinase Beta
(Gene symbol: PI4KB)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
2
2
SULFATE IONSULFATE ION
3
1
~{N}-[5-[3-[[(4-hydroxyphenyl)amino]-bis(oxidanyl)-$l^{4}-sulfanyl]-4-methoxy-phenyl]-4-methyl-1,3-thiazol-2-yl]cyclopentanecarboxamide~{N}-[5-[3-[[(4-hydroxyphenyl)amino]-bis(oxidanyl)-$l^{4}-sulfanyl]-4-methoxy-phenyl]-4-methyl-1,3-thiazol-2-yl]cyclopentanecarboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303