5EU8: Structure of FIPV main protease in complex with dual inhibitors

PDB ID: 5EU8Download
MMDB ID: 135211
PDB Deposition Date: 2015/11/18
Updated in MMDB: 2015/12
Experimental Method:
x-ray diffraction
Resolution: 2.447  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 5EU8: tetrameric; determined by author and by software (PISA)
Molecular Components in 5EU8
Label Count Molecule
Proteins (4 molecules)
2
Main Protease
Molecule annotation
2
N-[(5-methylisoxazol-3-yl)carbonyl]alanyl-l-valyl-n~1~-((1r,2z)-4-(benzyloxy)-4-oxo-1-{[(3r)-2-oxopyrrolidin-3-yl]methyl}but-2-enyl)-l-leucinamide
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
ZINC IONZINC ION
2
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303