5ESO: Crystal Structure of M. tuberculosis MenD with ThDP, Mg2+ and Isochorismate bound

PDB ID: 5ESODownload
MMDB ID: 140238
PDB Deposition Date: 2015/11/16
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 2.05  Å
Source Organism:
Similar Structures:
Biological Unit for 5ESO: tetrameric; determined by author and by software (PISA)
Molecular Components in 5ESO
Label Count Molecule
Proteins (4 molecules)
4
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate Synthase
(Gene symbol: menD)
Molecule annotation
Chemicals and Non-standard biopolymers (19 molecules)
1
4
MAGNESIUM IONMAGNESIUM ION
2
2
(5S,6S)-5-[(1-carboxyethenyl)oxy]-6-hydroxycyclohexa-1,3-diene-1-carboxylic acid(5S,6S)-5-[(1-carboxyethenyl)oxy]-6-hydroxycyclohexa-1,3-diene-1-carboxylic acid
3
6
FORMIC ACIDFORMIC ACID
4
3
GLYCEROLGLYCEROL
5
2
THIAMINE DIPHOSPHATETHIAMINE DIPHOSPHATE
6
2
BETA-MERCAPTOETHANOLBETA-MERCAPTOETHANOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303