5EOL: Crystal structure of human Pim-1 kinase in complex with a macrocyclic quinoxaline-pyrrolodihydropiperidinone inhibitor

PDB ID: 5EOLDownload
MMDB ID: 138924
PDB Deposition Date: 2015/11/10
Updated in MMDB: 2016/05
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 5EOL: monomeric; determined by author and by software (PISA)
Molecular Components in 5EOL
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase Pim-1
(Gene symbol: PIM1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
macrocyclic quinoxaline-pyrrolodihydropiperidinonemacrocyclic quinoxaline-pyrrolodihydropiperidinone
2
2
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303