5EK9: Crystal structure of the second bromodomain of human BRD2 in complex with a tetrahydroquinoline inhibitor

PDB ID: 5EK9Download
MMDB ID: 144907
PDB Deposition Date: 2015/11/3
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 2.08  Å
Source Organism:
Similar Structures:
Biological Unit for 5EK9: monomeric; determined by author
Molecular Components in 5EK9
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 2
(Gene symbol: BRD2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
propan-2-yl ~{N}-[(2~{S},4~{R})-1-ethanoyl-6-(furan-2-yl)-2-methyl-3,4-dihydro-2~{H}-quinolin-4-yl]carbamatepropan-2-yl ~{N}-[(2~{S},4~{R})-1-ethanoyl-6-(furan-2-yl)-2-methyl-3,4-dihydro-2~{H}-quinolin-4-yl]carbamate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303