5EHL: Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle kinase 1 (MPS1) Using a Structure-Based Hydridization Approach

PDB ID: 5EHLDownload
MMDB ID: 144652
PDB Deposition Date: 2015/10/28
Updated in MMDB: 2016/11
Experimental Method:
x-ray diffraction
Resolution: 2.66  Å
Source Organism:
Similar Structures:
Biological Unit for 5EHL: monomeric; determined by software (PISA)
Molecular Components in 5EHL
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Protein Kinase TTK
(Gene symbol: TTK)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]urea1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]urea
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303