5EG3: Crystal Structure of the Activated FGF Receptor 2 (FGFR2) Kinase Domain in complex with the cSH2 domain of Phospholipase C gamma (PLCgamma)

PDB ID: 5EG3Download
MMDB ID: 136254
PDB Deposition Date: 2015/10/26
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.606  Å
Source Organism:
Rattus norvegicus▼
Similar Structures:
Biological Unit for 5EG3: dimeric; determined by author and by software (PISA)
Molecular Components in 5EG3
Label Count Molecule
Proteins (2 molecules)
1
Fibroblast Growth Factor Receptor 2
Molecule annotation
1
1-phosphatidylinositol 4,5-bisphosphate Phosphodiesterase Gamma-1
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTERPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
2
2
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303