5EFK: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 (Y745F mutant) in complex with alpha tubulin K40 tripeptide substrate

PDB ID: 5EFKDownload
MMDB ID: 141303
PDB Deposition Date: 2015/10/23
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.82  Å
Source Organism:
Similar Structures:
Biological Unit for 5EFK: dimeric; determined by author and by software (PISA)
Molecular Components in 5EFK
Label Count Molecule
Proteins (2 molecules)
1
Hdac6 Protein
(Gene symbol: hdac6)
Molecule annotation
1
Alpha Tubulin K40 Tripeptide
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
1
ZINC IONZINC ION
2
2
POTASSIUM IONPOTASSIUM ION
3
1
GLYCEROLGLYCEROL
4
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
5
1
NITRATE IONNITRATE ION
6
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
7
1
7-AMINO-4-METHYL-CHROMEN-2-ONE7-AMINO-4-METHYL-CHROMEN-2-ONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303