5ECX: Klebsiella pneumoniae DfrA1 complexed with NADPH and 6-ethyl-5-(3-(6-(pyridin-4-yl)benzo[d][1,3]dioxol-4-yl)but-1-yn-1-yl)pyrimidine-2,4-diamine

PDB ID: 5ECXDownload
MMDB ID: 139310
PDB Deposition Date: 2015/10/20
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.95  Å
Source Organism:
Similar Structures:
Biological Unit for 5ECX: dimeric; determined by author and by software (PISA)
Molecular Components in 5ECX
Label Count Molecule
Proteins (2 molecules)
2
Dehydrofolate Reductase Type I
(Gene symbol: dfrA1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
2
6-ethyl-5-[(3~{S})-3-(6-pyridin-4-yl-1,3-benzodioxol-4-yl)but-1-ynyl]pyrimidine-2,4-diamine6-ethyl-5-[(3~{S})-3-(6-pyridin-4-yl-1,3-benzodioxol-4-yl)but-1-ynyl]pyrimidine-2,4-diamine
3
1
GLYCEROLGLYCEROL
4
1
GLYOXYLIC ACIDGLYOXYLIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303