5EBZ: Crystal structure of human IKK1

PDB ID: 5EBZDownload
MMDB ID: 144480
PDB Deposition Date: 2015/10/20
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 4.5  Å
Source Organism:
Similar Structures:
Biological Unit for 5EBZ: hexameric; determined by author and by software (PISA)
Molecular Components in 5EBZ
Label Count Molecule
Proteins (6 molecules)
6
Inhibitor of Nuclear Factor Kappa-b Kinase Subunit Alpha
(Gene symbol: CHUK)
Molecule annotation
Chemicals and Non-standard biopolymers (57 molecules)
1
14
2,4-di-O-sulfo-alpha-D-glucopyranose2,4-di-O-sulfo-alpha-D-glucopyranose
2
13
alpha-D-glucopyranosealpha-D-glucopyranose
3
14
2,3-di-O-sulfo-alpha-D-glucopyranose2,3-di-O-sulfo-alpha-D-glucopyranose
4
3
[(2R,3R,4R,5R,6S)-2-(hydroxymethyl)-5,6-bis(oxidanyl)-3-oxidanylsulfanyloxy-oxan-4-yl] hydrogen sulfate[(2R,3R,4R,5R,6S)-2-(hydroxymethyl)-5,6-bis(oxidanyl)-3-oxidanylsulfanyloxy-oxan-4-yl] hydrogen sulfate
5
1
[(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-2,5-bis(oxidanyl)-4-oxidanylsulfanyloxy-oxan-3-yl] hydrogen sulfate[(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-2,5-bis(oxidanyl)-4-oxidanylsulfanyloxy-oxan-3-yl] hydrogen sulfate
6
2
2-O-sulfo-alpha-D-glucopyranose2-O-sulfo-alpha-D-glucopyranose
7
2
(2S,3R,4R,5S,6R)-6-(hydroxymethyl)-5-oxidanylsulfanyloxy-oxane-2,3,4-triol(2S,3R,4R,5S,6R)-6-(hydroxymethyl)-5-oxidanylsulfanyloxy-oxane-2,3,4-triol
8
2
[(2S,3R,4S,5S,6R)-6-(hydroxymethyl)-2,4-bis(oxidanyl)-5-oxidanylsulfanyloxy-oxan-3-yl] hydrogen sulfate[(2S,3R,4S,5S,6R)-6-(hydroxymethyl)-2,4-bis(oxidanyl)-5-oxidanylsulfanyloxy-oxan-3-yl] hydrogen sulfate
9
6
2-azanyl-5-phenyl-3-(4-sulfamoylphenyl)benzamide2-azanyl-5-phenyl-3-(4-sulfamoylphenyl)benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303