5EBV: Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor 11c and CoA

PDB ID: 5EBVDownload
MMDB ID: 137902
PDB Deposition Date: 2015/10/19
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 5EBV: hexameric; determined by author and by software (PISA)
Molecular Components in 5EBV
Label Count Molecule
Proteins (6 molecules)
6
Enhanced Intracellular Survival Protein
(Gene symbol: eis)
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
6
COENZYME ACOENZYME A
2
6
5-(4-chlorophenyl)-~{N}-[3-(3,4-dihydro-1~{H}-isoquinolin-2-yl)propyl]-4-methyl-1,1-bis(oxidanylidene)-1,2-thiazol-3-amine5-(4-chlorophenyl)-~{N}-[3-(3,4-dihydro-1~{H}-isoquinolin-2-yl)propyl]-4-methyl-1,1-bis(oxidanylidene)-1,2-thiazol-3-amine
3
6
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303