5EA5: Crystal Structure of Inhibitor TMC-353121 in Complex with Prefusion RSV F Glycoprotein

PDB ID: 5EA5Download
MMDB ID: 134736
PDB Deposition Date: 2015/10/15
Updated in MMDB: 2015/12
Experimental Method:
x-ray diffraction
Resolution: 3.05  Å
Source Organism:
Similar Structures:
Biological Unit for 5EA5: trimeric; determined by author and by software (PISA)
Molecular Components in 5EA5
Label Count Molecule
Proteins (3 molecules)
3
Fusion Glycoprotein F0
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
3
2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID
2
1
2-[[6-[[[2-(3-hydroxypropyl)-5-methylphenyl]amino]methyl]-2-[[3-(4-morpholinyl)propyl]amino]-1H-benzimidazol-1-yl]methyl]-6-methyl-3-pyridinol2-[[6-[[[2-(3-hydroxypropyl)-5-methylphenyl]amino]methyl]-2-[[3-(4-morpholinyl)propyl]amino]-1H-benzimidazol-1-yl]methyl]-6-methyl-3-pyridinol
3
3
SULFATE IONSULFATE ION
4
3
D(-)-TARTARIC ACIDD(-)-TARTARIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303