5E8Q: Crystal structure of DHFR in 20% Isopropanol

PDB ID: 5E8QDownload
MMDB ID: 143233
PDB Deposition Date: 2015/10/14
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 5E8Q: monomeric; determined by author and by software (PISA)
Molecular Components in 5E8Q
Label Count Molecule
Protein (1 molecule)
1
Dihydrofolate Reductase
(Gene symbol: folA)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
FOLIC ACIDFOLIC ACID
2
1
ISOPROPYL ALCOHOLISOPROPYL ALCOHOL
3
1
CALCIUM IONCALCIUM ION
4
3
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303