5E8E: Crystal structure of thrombin bound to an exosite 1-specific IgA Fab

PDB ID: 5E8EDownload
MMDB ID: 133802
PDB Deposition Date: 2015/10/14
Updated in MMDB: 2016/10
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 5E8E: tetrameric; determined by author and by software (PISA)
Molecular Components in 5E8E
Label Count Molecule
Proteins (4 molecules)
1
IGA FAB Light Chain
Molecule annotation
1
IGA FAB Heavy Chain
Molecule annotation
1
Thrombin Heavy Chain
(Gene symbol: F2)
Molecule annotation
1
Thrombin Light Chain
(Gene symbol: F2)
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
1
5
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
beta-D-mannopyranosebeta-D-mannopyranose
3
1
alpha-D-mannopyranosealpha-D-mannopyranose
4
1
beta-D-galactopyranosebeta-D-galactopyranose
5
1
N-acetyl-alpha-neuraminic acidN-acetyl-alpha-neuraminic acid
6
3
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
7
5
PHOSPHATE IONPHOSPHATE ION
8
1
CITRIC ACIDCITRIC ACID
9
1
SODIUM IONSODIUM ION
10
1
D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamideD-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303