5E83: CRYSTAL STRUCTURE OF CARBONMONOXY HEMOGLOBIN S (LIGANDED SICKLE CELL HEMOGLOBIN) COMPLEXED WITH GBT440, CO-CRYSTALLIZATION EXPERIMENT

PDB ID: 5E83Download
MMDB ID: 140728
PDB Deposition Date: 2015/10/13
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 5E83: tetrameric; determined by author
Molecular Components in 5E83
Label Count Molecule
Proteins (4 molecules)
2
Hemoglobin Subunit Alpha
(Gene symbol: HBA1)
Molecule annotation
2
Hemoglobin Subunit Beta
(Gene symbol: HBB)
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
4
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
4
CARBON MONOXIDECARBON MONOXIDE
3
1
2-methyl-3-({2-[1-(propan-2-yl)-1H-pyrazol-5-yl]pyridin-3-yl}methoxy)phenol2-methyl-3-({2-[1-(propan-2-yl)-1H-pyrazol-5-yl]pyridin-3-yl}methoxy)phenol
4
3
GLYCEROLGLYCEROL
5
1
UNKNOWN LIGANDUNKNOWN LIGAND
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303