5E7R: Crystal structure of TL10-81 bound to TAK1-TAB1

PDB ID: 5E7RDownload
MMDB ID: 143232
PDB Deposition Date: 2015/10/13
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.11  Å
Source Organism:
Similar Structures:
Biological Unit for 5E7R: monomeric; determined by author and by software (PISA)
Molecular Components in 5E7R
Label Count Molecule
Protein (1 molecule)
1
Tak1 Kinase - Tab1 Chimera Fusion Protein
(Gene symbol: MAP3K7)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-chloro-N-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}acetamide2-chloro-N-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}acetamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303