5DY5: Crystal structure of human Sirt2 in complex with a SirReal probe fragment

PDB ID: 5DY5Download
MMDB ID: 135764
PDB Deposition Date: 2015/9/24
Updated in MMDB: 2016/02
Experimental Method:
x-ray diffraction
Resolution: 1.95  Å
Source Organism:
Similar Structures:
Biological Unit for 5DY5: dimeric; determined by author and by software (PISA)
Molecular Components in 5DY5
Label Count Molecule
Proteins (2 molecules)
2
Nad-dependent Protein Deacetylase Sirtuin-2
(Gene symbol: SIRT2)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
ZINC IONZINC ION
2
2
N-(5-{3-[(1-benzyl-1H-1,2,3-triazol-4-yl)methoxy]benzyl}-1,3-thiazol-2-yl)-2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetamideN-(5-{3-[(1-benzyl-1H-1,2,3-triazol-4-yl)methoxy]benzyl}-1,3-thiazol-2-yl)-2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetamide
3
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
2
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
5
2
(R,R)-2,3-BUTANEDIOL(R,R)-2,3-BUTANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303