5DU5: Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a dichloro-substituted, 3,4-diarylthiophene dioxide core ligand

PDB ID: 5DU5Download
MMDB ID: 138860
PDB Deposition Date: 2015/9/18
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.195  Å
Source Organism:
Similar Structures:
Biological Unit for 5DU5: tetrameric; determined by author and by software (PISA)
Molecular Components in 5DU5
Label Count Molecule
Proteins (4 molecules)
2
Estrogen Receptor
(Gene symbol: ESR1)
Molecule annotation
2
Nuclear Receptor Coactivator 2
(Gene symbol: NCOA2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
3,4-bis(2-chloro-4-hydroxyphenyl)-1H-1lambda~6~-thiophene-1,1-dione3,4-bis(2-chloro-4-hydroxyphenyl)-1H-1lambda~6~-thiophene-1,1-dione
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303