5DTM: Crystal structure of Dot1L in complex with inhibitor CPD1 [4-(2,6-dichlorobenzoyl)-N-methyl-1H-pyrrole-2-carboxamide]

PDB ID: 5DTMDownload
MMDB ID: 140064
PDB Deposition Date: 2015/9/18
Updated in MMDB: 2016/09
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 5DTM: monomeric; determined by author and by software (PISA)
Molecular Components in 5DTM
Label Count Molecule
Protein (1 molecule)
1
Histone-lysine N-methyltransferase, H3 Lysine-79 Specific
(Gene symbol: DOT1L)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
4-(2,6-dichlorobenzoyl)-N-methyl-1H-pyrrole-2-carboxamide4-(2,6-dichlorobenzoyl)-N-methyl-1H-pyrrole-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303